Why is a central venous catheter preferred for TPN?

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Multiple Choice

Why is a central venous catheter preferred for TPN?

Explanation:
The main idea is that TPN uses highly concentrated, hyperosmolar solutions that must be given into a central vein. Peripheral veins can’t tolerate such osmolality without causing irritation or vein injury, so they would be prone to phlebitis or extravasation. A central venous catheter delivers the solution into a large central vein where the high osmolar load is rapidly diluted by the great blood flow, making administration safer and feasible for long-term use. This setup also accommodates lipid emulsions and other components of TPN.

The main idea is that TPN uses highly concentrated, hyperosmolar solutions that must be given into a central vein. Peripheral veins can’t tolerate such osmolality without causing irritation or vein injury, so they would be prone to phlebitis or extravasation. A central venous catheter delivers the solution into a large central vein where the high osmolar load is rapidly diluted by the great blood flow, making administration safer and feasible for long-term use. This setup also accommodates lipid emulsions and other components of TPN.

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